Xeno's Pizza - The Best Pizza Slices in Midtown East NYC

Xeno's Pizza, opened in summer 2022, brings together decades of expertise from three partners with backgrounds in both quick service and fine dining. Known for our top-rated plain slice in NYC, we serve delicious pizza pies, slices, sandwiches, and more—all made with the finest ingredients, including our own fresh mozzarella crafted in-house daily. Xeno's offers quick counter service and a relaxed atmosphere where you can enjoy high-quality food fast. Whether you're dining in or grabbing a quick bite, we’re dedicated to delivering flavor and excellence with every order.

Xeno's Pizza - The Best Pizza Slices in Midtown East NYC is a pizza restaurant in New York, New York. It is listed at 163 E 52nd St, New York, NY 10022, which places it among the local businesses of New York that residents and visitors turn to when they need this kind of service close by. Besides its main category, the business also describes itself as caterer, chicken wings restaurant, italian restaurant, so it may cover more than the name suggests.

In New York, the busiest hours are Friday and Saturday evenings and any night with a big game, when quoted delivery times can stretch past an hour; ordering before 5 p.m. or picking up yourself avoids the wait. Delivery radiuses are small, often two to five miles, and a minimum order plus a delivery fee is normal, with a tip of a few dollars for the driver on top. Lunch specials such as two slices and a drink, or a personal pie, are the cheapest way to eat at most shops across New York on weekdays. Toppings are priced per item and half-and-half pies are usually free to request. Gluten-free crusts and vegan cheese are increasingly common but often cost a few dollars extra, and cross-contact in a shared oven is standard unless the shop says otherwise.

Hours are published for 2 days a week. Typical hours are 10:30 AM–10 PM. Hours in the United States do change around federal holidays and long weekends, so a quick call before a special trip is sensible. You can reach Xeno's Pizza - The Best Pizza Slices in Midtown East NYC at (646) 952-0030; calling is usually the quickest way to ask about availability, prices or directions. Its website is xenospizza.com, where you may find menus, price lists or booking options.

Customers rate it 4.3 out of 5 on Google across 234 reviews, placing it among the better-regarded pizza restaurants in New York.

New York is in New York, in the Northeast, where four distinct seasons shape local life: hot humid summers, snowy winters that can close businesses for a day, and a dense pattern of towns where walking, transit and street parking all matter. Traffic in New York peaks on weekday mornings and afternoons, so allow extra time then. Addresses read from the street number up to the city, state abbreviation and five-digit ZIP code; the map link on this page shows the exact spot.

Looking for alternatives? Browse all pizza restaurants in New York or explore other categories in the area from the links below. If you own or manage Xeno's Pizza - The Best Pizza Slices in Midtown East NYC, you can claim this listing to correct details, add photos and a description, and receive a verified badge. Everyone else can help by leaving an honest review on Google after a visit.